Frekuensi Relatif Melanoma Maligna di RSUP Dr Kariadi Semarang Selama Lima Tahun (1991 – 1995)

Tahun 1997 Volume 32 Nomor 1
Oleh : Afrida
Hanum, MM
Yustin, TM Sri Redjeki S, Indra Wijaya


Malignant melanoma (MM) is one of skin malignant tumor having metastatic and recurrence potency. A retrospective study of 5 years (1991 – 1995) to all patient histopathologically diagnosed as MM has been done, to find out the relative frequency of MM based on age, sex, tumor site, area of residence, correlation of clinical and histopathology diagnosis, depth of tumor invasion, type of MM, and comparation between clinical and histopatology diagnosis at Dr Kariadi Hospital Semarang . From this study we found 15 cases of MM, mostly women (10 cases), and the ratio between men and women was 10 : 5. The most frequent site of tumor was on the cheek, found in 5 cases (33.33%), and sun exposed area have a higher frequency than unexposed area 67% vs 33%. MM was found mostly in people who live at the seashore area (80%) as compare with the highland area. The depth of tumor invasion mostly are Clark”s level V found in 67% of 10 cases. Eighty seven percent of the type of MM are nodular melanoma. Analysis of diagnostic test with a gold standard of histopathological diagnosis in this study showed a sensitivity of 86%, specificity of 97%, positive predictive value of 43%, negative predictive value of 99% and accuracy of 97%.